A crucial role for maternal dietary methyl donor intake in epigenetic programming and fetal growth outcomes 

McGee, M., Bainbridge, S., & Fontaine-Bisson, B.

Nutrition reviews76(6), 469-478. doi: 10.1093/nutrit/nuy006 Epub 2018 June 1

PMID: 29529267

Vaccinium angustifolium (lowbush blueberry) leaf extract increases extravillous trophoblast cell migration and invasion in vitro.

Ly, C., Ferrier, J., Gaudet, J., Yockell‐Lelièvre, J., Arnason, J., Gruslin, A., Bainbridge, S.

Phytotherapy Research 32.4 (2018): 705-714. doi: 10.1002/ptr.6021. Epub 2018 Jan 29.

PMID: 29377302


Epigenetic regulation of placental gene expression in transcriptional subtypes of preeclampsia

Leavey K, Wilson SL, Bainbridge SA, Robinson WP, Cox BJ.

Clin Epigenetics. 2018 Mar 2;10:28. doi: 10.1186/s13148-018-0463-6. eCollection 2018.

PMID: 29507646


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Gene markers of normal villous maturation and their expression in placentas with maturational pathology.

Leavey K, Benton SJ, Grynspan D, Bainbridge SA, Morgen EK, Cox BJ.

Placenta. 2017 Oct;58:52-59. doi: 10.1016/j.placenta.2017.08.005. Epub 2017 Aug 12.

PMID: 28962696


A role for maternally derived myokines to optimize placental function and fetal growth across gestation.

Dubé C, Aguer C, Adamo K, Bainbridge S.

Appl Physiol Nutr Metab. 2017 May;42(5):459-469. doi: 10.1139/apnm-2016-0446. Epub 2017 Jan 17.

PMID: 28177716




Andrée Gruslin award lecture: Metabolomics as an important modality to better understand preeclampsia.

Benton SJ, Ly C, Vukovic S, Bainbridge SA.

Placenta. 2016 Nov 16. pii: S0143-4004(16)30626-9. doi: 10.1016/j.placenta.2016.11.006. [Epub ahead of print]

PMID: 27889063



Unsupervised Placental Gene Expression Profiling Identifies Clinically Relevant Subclasses of Human Preeclampsia.

Leavey K, Benton SJ, Grynspan D, Kingdom JC, Bainbridge SA, Cox BJ.

Hypertension. 2016;

PubMed [journal]   PMID: 2716020


Oocyte donation pregnancies and the risk of preeclampsia or gestational hypertension: a systematic review and metaanalysis.

Masoudian P, Nasr A, de Nanassy J, Fung-Kee-Fung K, Bainbridge SA, El Demellawy D.

American journal of obstetrics and gynecology. 2016; 214(3):328-39

PubMed [journal]   PMID: 26627731

Effect of folic acid on human trophoblast health and function in vitro.

Ahmed T, Fellus I, Gaudet J, MacFarlane AJ, Fontaine-Bisson B, Bainbridge SA.

Placenta. 2016; 37:7-15.

PubMed [journal]   PMID: 26748157


IFPA meeting 2015 workshop report: Mechanistic role of the placenta in fetal programming; biomarkers of placental function and complications of pregnancy; late onset fetal growth restriction surveillance and monitoring.

Andraweera PH, Bobek G, Bowen C, Burton GJ, Correa Frigerio P, Chaparro A, Dickinson H, Duncombe G, Hyett J, Illanes SE, Johnstone E, Kumar S, Morgan TK, Myers J, Orefice R, Roberts CT, Salafia CM, Thornburg KL, Whitehead CL, Bainbridge SA.

Placenta. 2015;

PubMed [journal]   PMID: 26733365

Large scale aggregate microarray analysis reveals three distinct molecular subclasses of human preeclampsia.

Leavey K, Bainbridge SA, Cox BJ.

PloS one. 2015; 10(2):e0116508.

PubMed [journal]   PMID: 25679511   PMCID: PMC4332506


IFPA Meeting 2013 Workshop Report I: diabetes in pregnancy, maternal dyslipidemia in pregnancy, oxygen in placental development, stem cells and pregnancy pathology.

Abumaree MH, Alahari S, Albrecht C, Aye IL, Bainbridge S, Chauvin S, Clifton VL, Desoye G, Ermini L, Giuffrida D, Graham CH, Huang QT, Kalionis B, Lager S, Leach L, Li Y, Litvack ML, Nuzzo AM, Moretto-Zita M, O'Tierney-Ginn P, Powell T, Rolfo A, Salomon C, Serov A, Westwood M, Yung HW, Lash GE.

Placenta. 2014; 35 Suppl:S4-9.

PubMed [journal]   PMID: 24321782


Endothelial NO synthase augments fetoplacental blood flow, placental vascularization, and fetal growth in mice.

Kulandavelu S, Whiteley KJ, Bainbridge SA, Qu D, Adamson SL.

Hypertension. 2013; 61(1):259-66.

PubMed [journal]   PMID: 23150513



Significance of IGFBP-4 in the development of fetal growth restriction.

Qiu Q, Bell M, Lu X, Yan X, Rodger M, Walker M, Wen SW, Bainbridge S, Wang H, Gruslin A.

The Journal of clinical endocrinology and metabolism. 2012; 97(8):E1429-39.

PubMed [journal]   PMID: 22689691

Endothelial nitric oxide synthase deficiency reduces uterine blood flow, spiral artery elongation, and placental oxygenation in pregnant mice.

Kulandavelu S, Whiteley KJ, Qu D, Mu J, Bainbridge SA, Adamson SL.

Hypertension. 2012; 60(1):231-8.

PubMed [journal]   PMID: 22615111

Effects of reduced Gcm1 expression on trophoblast morphology, fetoplacental vascularity, and pregnancy outcomes in mice.

Bainbridge SA, Minhas A, Whiteley KJ, Qu D, Sled JG, Kingdom JC, Adamson SL.

Hypertension. 2012; 59(3):732-9.

PubMed [journal]   PMID: 22275534


Uric acid attenuates trophoblast invasion and integration into endothelial cell monolayers.

Bainbridge SA, Roberts JM, von Versen-Höynck F, Koch J, Edmunds L, Hubel CA.

American journal of physiology. Cell physiology. 2009; 297(2):C440-50.

PubMed [journal]   PMID: 19535510   PMCID: PMC2724097

Increased xanthine oxidase in the skin of preeclamptic women.

Bainbridge SA, Deng JS, Roberts JM.

Reproductive sciences (Thousand Oaks, Calif.). 2009; 16(5):468-78. NIHMSID: NIHMS251714

PubMed [journal]   PMID: 19196876   PMCID: PMC2992872

Human placental adenosine receptor expression is elevated in preeclampsia and hypoxia increases expression of the A2A receptor.

von Versen-Höynck F, Rajakumar A, Bainbridge SA, Gallaher MJ, Roberts JM, Powers RW.

Placenta. 2009; 30(5):434-42. NIHMSID: NIHMS100410

PubMed [journal]   PMID: 19303140   PMCID: PMC2674514

Uric acid inhibits placental system A amino acid uptake.

Bainbridge SA, von Versen-Höynck F, Roberts JM.

Placenta. 2009; 30(2):195-200. NIHMSID: NIHMS107438

PubMed [journal]   PMID: 19058847   PMCID: PMC2677697


Uric acid as a pathogenic factor in preeclampsia.

Bainbridge SA, Roberts JM.

Placenta. 2008; 29 Suppl A:S67-72. NIHMSID: NIHMS45160

PubMed [journal]   PMID: 18093648   PMCID: PMC3319018

Diagnosis, evaluation, and management of the hypertensive disorders of pregnancy.

Magee LA, Helewa M, Moutquin JM, von Dadelszen P.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC. 2008; 30(3 Suppl):S1-48.

PubMed [journal]   PMID: 18817592


Glyceryl trinitrate inhibits hypoxia/reoxygenation-induced apoptosis in the syncytiotrophoblast of the human placenta: therapeutic implications for preeclampsia.

Belkacemi L, Bainbridge SA, Dickinson MA, Smith GN, Graham CH.

The American journal of pathology. 2007; 170(3):909-20.

PubMed [journal]   PMID: 17322376   PMCID: PMC1864864


Carbon monoxide inhibits hypoxia/reoxygenation-induced apoptosis and secondary necrosis in syncytiotrophoblast.

Bainbridge SA, Belkacemi L, Dickinson M, Graham CH, Smith GN.

The American journal of pathology. 2006; 169(3):774-83.

PubMed [journal]   PMID: 16936254   PMCID: PMC1698837

The effect of nicotine on in vitro placental perfusion pressure.

Bainbridge SA, Smith GN.

Canadian journal of physiology and pharmacology. 2006; 84(8-9):953-7.

PubMed [journal]   PMID: 17111041


HO in pregnancy.

Bainbridge SA, Smith GN.

Free radical biology & medicine. 2005; 38(8):979-88.

PubMed [journal]   PMID:15780756

Direct placental effects of cigarette smoke protect women from pre-eclampsia: the specific roles of carbon monoxide and antioxidant systems in the placenta.

Bainbridge SA, Sidle EH, Smith GN.

Medical hypotheses. 2005; 64(1):17-27.

PubMed [journal]   PMID: 15533604


Carbon monoxide decreases perfusion pressure in isolated human placenta.

Bainbridge SA, Farley AE, McLaughlin BE, Graham CH, Marks GS, Nakatsu K, Brien JF, Smith GN.

Placenta. 2002; 23(8-9):563-9.

PubMed [journal]   PMID: 12361675